BTNL2 (Butyrophilin-like Protein 2, BTL-II)

Antibodies / Antibodies-Enzymes

-20°C

Supplied as a liquid in PBS, 0.09% sodium azide, 50% glycerol.

Recombinant protein corresponding to human BTNL2.

BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455aa single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.

Applications:
Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.