Lysosome Associated Membrane Protein 2 (LAMP 2, Igp2, Igp110, CD107b, LAMP2C, LAMPB, Lysosome Associated Membrane Glycoprotein 2 Precursor, MAC3)

Antibodies / Antibodies-CD Markers

-20°C

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

Glycoproteins purified from mouse peritoneal macrophage membranes.

Murine CD107b, also known as MAC-3 and LAMP-2, is a transmembrane glycoprotein that is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. Expression of CD107b does vary between cell populations and the molecular weight of CD107b can vary between 92-120kD. Studies suggest that CD107b may be involved in leukocyte adhesion.

Applications:
Suitable for use in Flow Cytometry, Immunohistochemistry, Western Blot and Immunoprecipitation. Other applications not tested.

Recommended Dilutions:
Flow Cytometry: 1:50-1:100; 10ul labels 10e6 cells in 100ul. Membrane permeabilization is required,
Immunohistochemistry: Paraffin and frozen sections
Optimal dilutions to be determined by the researcher.

Hybridoma:
P3-NS1-Ag4-1 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.