ATG4B Rabbit pAb

ice pack

44kDa

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-393 of human ATG4B (NP_037457.3).

44kDa

Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Autophagy, Extracellular Matrix, Ubiquitin, Endocrine Metabolism, Mitochondrial metabolism, Cardiovascular, Heart.

23192

ATG4B