Vergleich

Anti-MMP16 Antibody

ArtNr ABC-ABO10578
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen WB, IHC-P, IHC-F
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MMP-16, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3-MMP, MT3MMP, MMP-X2, MMP16, MMPX2, Matrix metalloproteinase-16, 3.4.24.-
Lieferbar
Primary Accession
P51512
Application
WB, IHC-P, IHC-F
Clonality
Polyclonal
Gene ID
4325
Reactivity
H, M, Rat
Legend image 1
Anti-MMP16 antibody, ABO10578, Western blottingLane 1: HELA Cell LysateLane 2: COLO320 Cell Lysate
Type image 1
WB
Dilution image 1
0.1-0.5 µg/ml
Legend image 2
Anti-MMP16 antibody, ABO10578, IHC(P)IHC(P): Human Rectal Cancer Tissue
Type image 2
IHC
Dilution image 2
0.5-1 µg/ml
Calculated MW
69521
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description
Rabbit IgG polyclonal antibody for Matrix metalloproteinase-16(MMP16) detection. Tested with WB, IHC-P, IHC-F in Human; Mouse; Rat.
Protein Function
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. .
Subcellular Localization
Isoform Long: Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Localized at the cell surface of melanoma cells.
Tissue Specificity
Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
Protein Name
Matrix metalloproteinase-16(MMP-16)
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MMP16(582-598aa, YTVFQFKRKGTPRHILY), identical to the related rat and mouse sequences.
Purification
Immunogen affinity purified.
Cross Reactivity
No cross reactivity with other proteins
Storage
At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities
Belongs to the peptidase M10A family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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