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Anti-MMP16 Antibody

Anti-MMP16 Antibody

Item no.	ABC-ABO10578
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB, IHC-P, IHC-F
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	MMP-16, Membrane-type matrix metalloproteinase 3, MT-MMP 3, MTMMP3, Membrane-type-3 matrix metalloproteinase, MT3-MMP, MT3MMP, MMP-X2, MMP16, MMPX2, Matrix metalloproteinase-16, 3.4.24.-
Available
Primary Accession	P51512
Application	WB, IHC-P, IHC-F
Clonality	Polyclonal
Gene ID	4325
Reactivity	H, M, Rat
Legend image 1	Anti-MMP16 antibody, ABO10578, Western blottingLane 1: HELA Cell LysateLane 2: COLO320 Cell Lysate
Type image 1	WB
Dilution image 1	0.1-0.5 µg/ml
Legend image 2	Anti-MMP16 antibody, ABO10578, IHC(P)IHC(P): Human Rectal Cancer Tissue
Type image 2	IHC
Dilution image 2	0.5-1 µg/ml
Calculated MW	69521
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for Matrix metalloproteinase-16(MMP16) detection. Tested with WB, IHC-P, IHC-F in Human; Mouse; Rat.
Protein Function	Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. .
Subcellular Localization	Isoform Long: Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Localized at the cell surface of melanoma cells.
Tissue Specificity	Expressed in heart, brain, placenta, ovary and small intestine. Isoform Short is found in the ovary.
Protein Name	Matrix metalloproteinase-16(MMP-16)
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human MMP16(582-598aa, YTVFQFKRKGTPRHILY), identical to the related rat and mouse sequences.
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the peptidase M10A family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/6/2025

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