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SMAD4 antibody - middle region

ArtNr ABC-AI10038
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Sheep (Ovine, Ovis aries), Chicken (Gallus gallus domesticus), Cattle (Bovine)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Mothers against decapentaplegic homolog 4,MAD homolog 4,Mothers against DPP homolog 4,Deletion target in pancreatic carcinoma 4,SMAD family member 4,SMAD 4,Smad4,hSMAD4,SMAD4,DPC4,MADH4
Similar products SMAD4, Smad4, DPC4, MADH4, MAD homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, SMAD 4, hSMAD4
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Manufacturer - Targets
SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantly related to Smads 2 and 3, and forms a heteromeric complex with Smad2 after TGF-beta or activin stimulation. TGF-beta induces heteromeric complexes of Smads 2, 3 and 4, and their concomitant translocation to the nucleus, which is required for efficient TGF-beta signal transduction
Storage Conditions
Add 100 ul of distilled water. Final anti-SMAD4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Bio Background
This is a rabbit polyclonal antibody against SMAD4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
Clonality
Polyclonal
Gene Name
SMAD4
Subtitle
Rabbit Polyclonal Antibody
Reactivity
H, M, Rat, Rb, Ga, D, Gp, Hs, Sh, B
Predicted Reactivity
H, M, Rat, Pig, Ga, Gp, Hs, B
Calculated Molecular Weight
60439
Formulation
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen for anti-SMAD4 antibody: synthetic peptide directed towards the middle region of human SMAD4
Purification
Protein A purified
Protein Size
552
Partner Proteins
ACVR1, BCAT1, BMP6, CXXC5, FLNA, GDF6, HBG2, HOXA13, HOXD13, MBD1, MEN1, MTMR10, PNKP, PPIL4, PSMD11, PTPN12, RBM4, RYR2, SF3B1, SFPQ, SMAD1, SMAD4, SMURF2, SNRNP70, SNRPA, SOX5, SOX7, SUV39H1, SUV39H2, TOB1, U2AF2, VPS24, WWP1, ZEB2, ZNF8, ACVR1, PLEKHO1, RUNX1, RUNX2, RUNX3, SMAD4, SMURF1, TOB1
Nucleotide Accession Number
NM_005359
Protein Accession Number
NP_005350
Alias Symbol
JIP, DPC4, MADH4, MYHRS

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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