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SMAD4 antibody - middle region

SMAD4 antibody - middle region

Item no.	ABC-AI10038
Manufacturer	Abcepta
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Adenocarcinoma Western Blot Primary Antibodies By Organ Colorectal Cancer Neurodegeneration Markers
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Sheep (Ovine, Ovis aries), Chicken (Gallus gallus domesticus), Cattle (Bovine)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mothers against decapentaplegic homolog 4,MAD homolog 4,Mothers against DPP homolog 4,Deletion target in pancreatic carcinoma 4,SMAD family member 4,SMAD 4,Smad4,hSMAD4,SMAD4,DPC4,MADH4
Similar products	SMAD4, Smad4, DPC4, MADH4, MAD homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, SMAD 4, hSMAD4
Available
Manufacturer - Targets	SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantly related to Smads 2 and 3, and forms a heteromeric complex with Smad2 after TGF-beta or activin stimulation. TGF-beta induces heteromeric complexes of Smads 2, 3 and 4, and their concomitant translocation to the nucleus, which is required for efficient TGF-beta signal transduction
Storage Conditions	Add 100 ul of distilled water. Final anti-SMAD4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Bio Background	This is a rabbit polyclonal antibody against SMAD4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
Clonality	Polyclonal
Gene Name	SMAD4
Subtitle	Rabbit Polyclonal Antibody
Reactivity	H, M, Rat, Rb, Ga, D, Gp, Hs, Sh, B
Predicted Reactivity	H, M, Rat, Pig, Ga, Gp, Hs, B
Calculated Molecular Weight	60439
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen	The immunogen for anti-SMAD4 antibody: synthetic peptide directed towards the middle region of human SMAD4
Purification	Protein A purified
Protein Size	552
Partner Proteins	ACVR1, BCAT1, BMP6, CXXC5, FLNA, GDF6, HBG2, HOXA13, HOXD13, MBD1, MEN1, MTMR10, PNKP, PPIL4, PSMD11, PTPN12, RBM4, RYR2, SF3B1, SFPQ, SMAD1, SMAD4, SMURF2, SNRNP70, SNRPA, SOX5, SOX7, SUV39H1, SUV39H2, TOB1, U2AF2, VPS24, WWP1, ZEB2, ZNF8, ACVR1, PLEKHO1, RUNX1, RUNX2, RUNX3, SMAD4, SMURF1, TOB1
Nucleotide Accession Number	NM_005359
Protein Accession Number	NP_005350
Alias Symbol	JIP, DPC4, MADH4, MYHRS

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 3/5/2026

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