MMP2 Antibody

ArtNr	ABC-AM1844b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies By Cell Type Blastoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB, IF, IHC-P
Clon	6E3F8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Role of functional single nucleotide polymorphisms of MMP1, MMP2, and MMP9 in open angle glaucomas. Mossb??ck G, et al. Mol Vis, 2010 Aug 28. PMID 20808730. Clinical Impact of MMP and TIMP Gene Polymorphisms in Gastric Cancer. Alakus H, et al. World J Surg, 2010 Aug 21. PMID 20730428. A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Romero R, et al. Am J Obstet Gynecol, 2010 Jul 29. PMID 20673868. Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate. Nikopensius T, et al. Birth Defects Res A Clin Mol Teratol, 2010 Jul 29. PMID 20672350. [Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and clinical significance] Gou XX, et al. Zhonghua Yi Xue Za Zhi, 2010 May 11. PMID 20646600.
NCBI	NP_001121363.1,NP_004521.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	72 kDa type IV collagenase,72 kDa gelatinase,Gelatinase A,Matrix metalloproteinase-2,MMP-2,TBE-1,PEX,MMP2,CLG4A
Similar products	MMP-2, MMP2, CLG4A, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Metabolism
Manufacturer - Targets	This MMP2 monoclonal antibody is generated from mouse immunized with MMP2 recombinant protein.
Bio Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	MMP2
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	73882
Antigen Source	HUMAN
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	IF: 1:10~50 WB: 1:500~1000 IHC-P: 1:10~50 IHC-P: 1:10~50

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