ACTA1 Antibody

Primary Antibodies; Cancer; Cardiovascular; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies; Inflammation mediated by chemokine and cytokine signaling

The product encoded by this gene belongs to the actinfamily of proteins, which are highly conserved proteins that play arole in cell motility, structure and integrity. Alpha, beta andgamma actin isoforms have been identified, with alpha actins beinga major constituent of the contractile apparatus, while beta andgamma actins are involved in the regulation of cell motility. Thisactin is an alpha actin that is found in skeletal muscle. Mutationsin this gene cause nemaline myopathy type 3, congenital myopathywith excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseasesthat lead to muscle fiber defects.

ACTA1

H

42051

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Recombinant Protein