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IL1B Antibody (Center) (Ascites)

ArtNr ABC-AM2121a
Hersteller Abcepta
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Applikationen WB
Clon 614CT4.3.1
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Citations Lee, B., et al. J. Immunol. 185(10):5926-5934(2010)
Arana-Argaez, V.E., et al. J. Biol. Chem. 285(43):32824-32833(2010)
Zhang, Z., et al. J. Biol. Chem. 285(43):33092-33103(2010)
Wang, D., et al. Nat. Immunol. 11(10):905-911(2010)
Gein, O.N., et al. Patol Fiziol Eksp Ter 1, 10-13 (2010) :
NCBI NP_000567.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Interleukin-1 beta,IL-1 beta,Catabolin,IL1B,IL1F2
Similar products IL-1 beta, IL1B, IL1F2, Interleukin-1 beta, Catabolin
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Manufacturer - Category
Primary Antibodies; Cancer; Cardiovascular; Immunology; Metabolism; Neuroscience; Signal Transduction; Inflammasome; Inflammatory response; Toll-Like receptor signaling; Cytokine; Cytokine, IL-1-like; Inflammation mediated by chemokine and cytokine signaling; Lysosome; Pyroptosis
Manufacturer - Targets
This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.
Bio Background
The protein encoded by this gene is a member of theinterleukin 1 cytokine family. This cytokine is produced byactivated macrophages as a proprotein, which is proteolyticallyprocessed to its active form by caspase 1 (CASP1/ICE). Thiscytokine is an important mediator of the inflammatory response, andis involved in a variety of cellular activities, including cellproliferation, differentiation, and apoptosis. The induction ofcyclooxygenase-2 (PTGS2/COX2) by this cytokine in the centralnervous system (CNS) is found to contribute to inflammatory painhypersensitivity. This gene and eight other interleukin 1 familygenes form a cytokine gene cluster on chromosome 2. [provided byRefSeq].
Clonality
Monoclonal
Gene Name
IL1B
Subtitle
Mouse Monoclonal Antibody (Mab)
Reactivity
H
Predicted Reactivity
Pr, Rb
Calculated Molecular Weight
30748
Antigen Source
HUMAN
Antigen Region
148-174
Formulation
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Dilution
WB: 1:2000~4000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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