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IL1B Antibody (Center) (Ascites)

IL1B Antibody (Center) (Ascites)

Item no.	ABC-AM2121a
Manufacturer	Abcepta
Amount	100 ul
Category	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB
Clone	614CT4.3.1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	Lee, B., et al. J. Immunol. 185(10):5926-5934(2010) Arana-Argaez, V.E., et al. J. Biol. Chem. 285(43):32824-32833(2010) Zhang, Z., et al. J. Biol. Chem. 285(43):33092-33103(2010) Wang, D., et al. Nat. Immunol. 11(10):905-911(2010) Gein, O.N., et al. Patol Fiziol Eksp Ter 1, 10-13 (2010) :
NCBI	NP_000567.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Interleukin-1 beta,IL-1 beta,Catabolin,IL1B,IL1F2
Similar products	IL-1 beta, IL1B, IL1F2, Interleukin-1 beta, Catabolin
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Immunology; Metabolism; Neuroscience; Signal Transduction; Inflammasome; Inflammatory response; Toll-Like receptor signaling; Cytokine; Cytokine, IL-1-like; Inflammation mediated by chemokine and cytokine signaling; Lysosome; Pyroptosis
Manufacturer - Targets	This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.
Bio Background	The protein encoded by this gene is a member of theinterleukin 1 cytokine family. This cytokine is produced byactivated macrophages as a proprotein, which is proteolyticallyprocessed to its active form by caspase 1 (CASP1/ICE). Thiscytokine is an important mediator of the inflammatory response, andis involved in a variety of cellular activities, including cellproliferation, differentiation, and apoptosis. The induction ofcyclooxygenase-2 (PTGS2/COX2) by this cytokine in the centralnervous system (CNS) is found to contribute to inflammatory painhypersensitivity. This gene and eight other interleukin 1 familygenes form a cytokine gene cluster on chromosome 2. [provided byRefSeq].
Clonality	Monoclonal
Gene Name	IL1B
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Predicted Reactivity	Pr, Rb
Calculated Molecular Weight	30748
Antigen Source	HUMAN
Antigen Region	148-174
Formulation	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Dilution	WB: 1:2000~4000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/1/2026

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