PPARA Antibody

ArtNr	ABC-AM8425b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Metabolism Diabetes Glucose Homeostasis Antibodies Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Atherosclerosis Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB, FC, IF, IHC-P
Clon	1331CT894.186.143
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Sher T.,et al.Biochemistry 32:5598-5604(1993). Mukherjee R.,et al.J. Steroid Biochem. Mol. Biol. 51:157-166(1994). Tugwood J.D.,et al.Ann. N. Y. Acad. Sci. 804:252-265(1996). Kobayashi T.,et al.FEBS Lett. 582:2737-2744(2008). Cho M.-C.,et al.Immunopharmacol. Immunotoxicol. 31:459-467(2009).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Peroxisome proliferator-activated receptor alpha,PPAR-alpha,Nuclear receptor subfamily 1 group C member 1,PPARA,NR1C1,PPAR
Similar products	PPARA, NR1C1, PPAR, Peroxisome proliferator-activated receptor alpha, Nuclear receptor subfamily 1 group C member 1, PPAR-alpha
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Manufacturer - Category	Crown Antibodies; Primary Antibodies; Cancer; Cardiovascular; Metabolism; Toll-Like Receptor
Manufacturer - Targets	This PPARA antibody is generated from a mouse immunized with a recombination protein from the human region of human PPARA.
Bio Background	Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P45 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2.
Clonality	Monoclonal
Gene Name	PPARA
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H, M
Calculated Molecular Weight	52225
Antigen Source	HUMAN
Antigen Region	1-468
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	IF: 1:25 WB: 1:1000 IHC-P: 1:25 IHC-P: 1:25 FC: 1:25
Antigen Type	Recombinant Protein

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Menge: 80 ul

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