Vergleich

GALNT4 Antibody (N-term)

Hersteller Abcepta
Kategorie
Typ Antibody Primary
Specific against other
Isotype Ig
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB, FC
Menge 400 ul
Host Rabbit
ArtNr ABC-AP10190a
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Primary Accession
Q8N4A0
Antigen Type
Synthetic Peptide
Application
FC, WB
Bio Background
This gene encodes a member of the
UDP-N-acetyl-alpha-D-galactosamine:polypeptide
N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.
GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi
apparatus by catalyzing the transfer of GalNAc to serine and
threonine residues on target proteins. They are characterized by an
N-terminal transmembrane domain, a stem region, a lumenal catalytic
domain containing a GT1 motif and Gal/GalNAc transferase motif, and
a C-terminal ricin/lectin-like domain. GalNAc-Ts have different,
but overlapping, substrate specificities and patterns of
expression. In vitro, the encoded protein can complement other
GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem
repeat and can O-glycosylate the P-selectin glycoprotein ligand-1
molecule. The coding region of this gene is contained within a
single exon.
Bio References
O'Halloran, A.M., et al. J. Thromb. Thrombolysis 27(2):175-184(2009)
Argueso, P., et al. Invest. Ophthalmol. Vis. Sci. 44(1):86-92(2003)
Hassan, H., et al. J. Biol. Chem. 275(49):38197-38205(2000)
Bennett, E.P., et al. J. Biol. Chem. 273(46):30472-30481(1998)
Bennett, E.P., et al. Glycobiology 8(6):547-555(1998)
Clonality
Polyclonal
Clone/Animal Names
RB23943
Gene ID
100528030; 8693
Gene Name
GALNT4
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
GALNT4 Antibody (N-term) (Cat. #AP10190a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GALNT4 antibody detected the GALNT4 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
GALNT4 Antibody (N-term) (Cat. #AP10190a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2
FC
Dilution image 2
1:10~50
Other Accession
O08832; NP_003765.2
Predicted
M
Isotype
Rabbit Ig
Calculated MW
66666
Antigen Region
93-120
Antigen Source
HUMAN
Target/Specificity
This GALNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human GALNT4.
NCBI Accession
NP_001186711.1; NP_003765.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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Lieferung vsl. bis 06.06.2024 

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