Hersteller |
Abcepta
|
Kategorie |
|
Typ |
Antibody Primary |
Specific against |
other |
Isotype |
Ig |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB, FC |
Menge |
400 ul |
Host |
Rabbit |
ArtNr |
ABC-AP10190a |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Primary Accession |
Q8N4A0 |
Antigen Type |
Synthetic Peptide |
Application |
FC, WB |
Bio Background |
This gene encodes a member of theUDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgiapparatus by catalyzing the transfer of GalNAc to serine andthreonine residues on target proteins. They are characterized by anN-terminal transmembrane domain, a stem region, a lumenal catalyticdomain containing a GT1 motif and Gal/GalNAc transferase motif, anda C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns ofexpression. In vitro, the encoded protein can complement otherGalNAc-Ts in the complete O-glycosylation of the mucin-1 tandemrepeat and can O-glycosylate the P-selectin glycoprotein ligand-1molecule. The coding region of this gene is contained within asingle exon. |
Bio References |
O'Halloran, A.M., et al. J. Thromb. Thrombolysis 27(2):175-184(2009)Argueso, P., et al. Invest. Ophthalmol. Vis. Sci. 44(1):86-92(2003)Hassan, H., et al. J. Biol. Chem. 275(49):38197-38205(2000)Bennett, E.P., et al. J. Biol. Chem. 273(46):30472-30481(1998)Bennett, E.P., et al. Glycobiology 8(6):547-555(1998) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB23943 |
Gene ID |
100528030; 8693 |
Gene Name |
GALNT4 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
GALNT4 Antibody (N-term) (Cat. #AP10190a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GALNT4 antibody detected the GALNT4 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
GALNT4 Antibody (N-term) (Cat. #AP10190a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 2 |
FC |
Dilution image 2 |
1:10~50 |
Other Accession |
O08832; NP_003765.2 |
Predicted |
M |
Isotype |
Rabbit Ig |
Calculated MW |
66666 |
Antigen Region |
93-120 |
Antigen Source |
HUMAN |
Target/Specificity |
This GALNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human GALNT4. |
NCBI Accession |
NP_001186711.1; NP_003765.2 |
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