Manufacturer |
Abcepta
|
Category |
|
Type |
Antibody Primary |
Specific against |
other |
Isotype |
Ig |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, FC |
Amount |
400 ul |
Host |
Rabbit |
Item no. |
ABC-AP10190a |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Primary Accession |
Q8N4A0 |
Antigen Type |
Synthetic Peptide |
Application |
FC, WB |
Bio Background |
This gene encodes a member of theUDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes.GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgiapparatus by catalyzing the transfer of GalNAc to serine andthreonine residues on target proteins. They are characterized by anN-terminal transmembrane domain, a stem region, a lumenal catalyticdomain containing a GT1 motif and Gal/GalNAc transferase motif, anda C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns ofexpression. In vitro, the encoded protein can complement otherGalNAc-Ts in the complete O-glycosylation of the mucin-1 tandemrepeat and can O-glycosylate the P-selectin glycoprotein ligand-1molecule. The coding region of this gene is contained within asingle exon. |
Bio References |
O'Halloran, A.M., et al. J. Thromb. Thrombolysis 27(2):175-184(2009)Argueso, P., et al. Invest. Ophthalmol. Vis. Sci. 44(1):86-92(2003)Hassan, H., et al. J. Biol. Chem. 275(49):38197-38205(2000)Bennett, E.P., et al. J. Biol. Chem. 273(46):30472-30481(1998)Bennett, E.P., et al. Glycobiology 8(6):547-555(1998) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB23943 |
Gene ID |
100528030; 8693 |
Gene Name |
GALNT4 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
GALNT4 Antibody (N-term) (Cat. #AP10190a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the GALNT4 antibody detected the GALNT4 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
GALNT4 Antibody (N-term) (Cat. #AP10190a) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Type image 2 |
FC |
Dilution image 2 |
1:10~50 |
Other Accession |
O08832; NP_003765.2 |
Predicted |
M |
Isotype |
Rabbit Ig |
Calculated MW |
66666 |
Antigen Region |
93-120 |
Antigen Source |
HUMAN |
Target/Specificity |
This GALNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human GALNT4. |
NCBI Accession |
NP_001186711.1; NP_003765.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.