Hersteller |
Abcepta
|
Kategorie |
|
Typ |
Antibody Primary |
Specific against |
other |
Isotype |
Ig |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applikationen |
WB |
Menge |
400 ul |
Host |
Rabbit |
ArtNr |
ABC-AP10451b |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Primary Accession |
Q15389 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
Angiopoietins are proteins with important roles invascular development and angiogenesis. All angiopoietins bind withsimilar affinity to an endothelial cell-specific tyrosine-proteinkinase receptor. The protein encoded by this gene is a secretedglycoprotein that activates the receptor by inducing its tyrosinephosphorylation. It plays a critical role in mediating reciprocalinteractions between the endothelium and surrounding matrix andmesenchyme. The protein also contributes to blood vessel maturationand stability, and may be involved in early development of theheart. |
Bio References |
Fang, X., et al. J. Biol. Chem. 285(34):26211-26222(2010)Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Choe, J.Y., et al. Joint Bone Spine 77(4):340-344(2010)Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Chen, J., et al. Hum. Mol. Genet. 19(12):2524-2533(2010) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB17673 |
Gene ID |
284 |
Gene Name |
ANGPT1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Anti-ANGPT1 Antibody (C-term)at 1:2000 dilution + mouse lung lysatesLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 58 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:2000 |
Legend image 2 |
ANGPT1 Antibody (C-term) (Cat. #AP10451b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ANGPT1 antibody detected the ANGPT1 protein (arrow). |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Other Accession |
Q9BDY8; O08538; O18920; NP_001137.2 |
Predicted |
B, Pig |
Isotype |
Rabbit Ig |
Calculated MW |
57513 |
Antigen Region |
374-402 |
Antigen Source |
HUMAN |
Target/Specificity |
This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1. |
NCBI Accession |
NP_001137.2; NP_001186788.1 |
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