Manufacturer |
Abcepta
|
Category |
|
Type |
Antibody Primary |
Specific against |
other |
Isotype |
Ig |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB |
Amount |
400 ul |
Host |
Rabbit |
Item no. |
ABC-AP10451b |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Primary Accession |
Q15389 |
Antigen Type |
Synthetic Peptide |
Application |
WB |
Bio Background |
Angiopoietins are proteins with important roles invascular development and angiogenesis. All angiopoietins bind withsimilar affinity to an endothelial cell-specific tyrosine-proteinkinase receptor. The protein encoded by this gene is a secretedglycoprotein that activates the receptor by inducing its tyrosinephosphorylation. It plays a critical role in mediating reciprocalinteractions between the endothelium and surrounding matrix andmesenchyme. The protein also contributes to blood vessel maturationand stability, and may be involved in early development of theheart. |
Bio References |
Fang, X., et al. J. Biol. Chem. 285(34):26211-26222(2010)Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)Choe, J.Y., et al. Joint Bone Spine 77(4):340-344(2010)Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)Chen, J., et al. Hum. Mol. Genet. 19(12):2524-2533(2010) |
Clonality |
Polyclonal |
Clone/Animal Names |
RB17673 |
Gene ID |
284 |
Gene Name |
ANGPT1 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H, M |
Legend image 1 |
Anti-ANGPT1 Antibody (C-term)at 1:2000 dilution + mouse lung lysatesLysates/proteins at 20 µg per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 58 kDaBlocking/Dilution buffer: 5% NFDM/TBST. |
Type image 1 |
WB |
Dilution image 1 |
1:2000 |
Legend image 2 |
ANGPT1 Antibody (C-term) (Cat. #AP10451b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ANGPT1 antibody detected the ANGPT1 protein (arrow). |
Type image 2 |
WB |
Dilution image 2 |
1:1000 |
Other Accession |
Q9BDY8; O08538; O18920; NP_001137.2 |
Predicted |
B, Pig |
Isotype |
Rabbit Ig |
Calculated MW |
57513 |
Antigen Region |
374-402 |
Antigen Source |
HUMAN |
Target/Specificity |
This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1. |
NCBI Accession |
NP_001137.2; NP_001186788.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.