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FOSL2 Antibody (Center)

FOSL2 Antibody (Center)

ArtNr	ABC-AP10972c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	FOSL2, FRA2, Fos-related antigen 2, FRA-2
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Primary Accession	P15408
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Bio References	Bozec, A., et al. J. Cell Biol. 190(6):1093-1106(2010) Bolat, I., et al. Folia Histochem. Cytobiol. 48(2):197-201(2010) Reich, N., et al. Arthritis Rheum. 62(1):280-290(2010) Maurer, B., et al. Circulation 120(23):2367-2376(2009) Tabakoff, B., et al. BMC Biol. 7, 70 (2009) :
Clonality	Polyclonal
Clone/Animal Names	RB24397
Gene ID	2355
Gene Name	FOSL2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, Ha
Legend image 1	FOSL2 Antibody (Center) (Cat. #AP10972c) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the FOSL2 antibody detected the FOSL2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Western blot analysis of lysate from Daudi cell line, using FOSL2 Antibody (Center)(Cat. #AP10972c). AP10972c was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	FOSL2 antibody (Center) (Cat. #AP10972c) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FOSL2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Other Accession	P51145; P47930; P18625; NP_005244.1
Predicted	C, M, Rat
Isotype	Rabbit Ig
Calculated MW	35193
Antigen Region	95-122
Antigen Source	HUMAN
Target/Specificity	This FOSL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from the Central region of human FOSL2.
NCBI Accession	NP_005244.1

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