Vergleich

IRAK4 Antibody (N-term)

ArtNr ABC-AP12875A
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IRAK-4, IRAK4, Interleukin-1 receptor-associated kinase 4, Renal carcinoma antigen NY-REN-64
Lieferbar
Primary Accession
Q9NWZ3
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
This gene encodes a kinase that activates NF-kappaB in
both the Toll-like receptor (TLR) and T-cell receptor (TCR)
signaling pathways. The protein is essential for most innate immune
responses. Mutations in this gene result in IRAK4 deficiency and
recurrent invasive pneumococcal disease. Multiple transcript
variants encoding different isoforms have been found for this gene.
Bio References
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
McDonald, D.R., et al. J. Allergy Clin. Immunol. 126(2):332-337(2010)
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Wang, Z., et al. Structure 14(12):1835-1844(2006)
Clonality
Polyclonal
Clone/Animal Names
RB33094
Gene ID
51135
Gene Name
IRAK4
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
IRAK4 Antibody (N-term) (Cat. #AP12875a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the IRAK4 antibody detected the IRAK4 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Anti-IRAK4 Antibody (N-term) at 1:1000 dilution + K562 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 52 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2
WB
Dilution image 2
1:1000
Other Accession
Q8R4K2; Q1RMT8; NP_001107654.1; NP_057207.2
Predicted
B, M
Isotype
Rabbit Ig
Calculated MW
51530
Antigen Region
25-52
Antigen Source
HUMAN
Target/Specificity
This IRAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human IRAK4.
NCBI Accession
NP_001107654.1; NP_001138728.1; NP_001138729.1; NP_001138730.1; NP_057207.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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