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IRAK4 Antibody (N-term)

IRAK4 Antibody (N-term)

Item no.	ABC-AP12875A
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	IRAK-4, IRAK4, Interleukin-1 receptor-associated kinase 4, Renal carcinoma antigen NY-REN-64
Available
Primary Accession	Q9NWZ3
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Bio References	Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) McDonald, D.R., et al. J. Allergy Clin. Immunol. 126(2):332-337(2010) Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010) Wang, Z., et al. Structure 14(12):1835-1844(2006)
Clonality	Polyclonal
Clone/Animal Names	RB33094
Gene ID	51135
Gene Name	IRAK4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	IRAK4 Antibody (N-term) (Cat. #AP12875a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the IRAK4 antibody detected the IRAK4 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Anti-IRAK4 Antibody (N-term) at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 52 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 2	WB
Dilution image 2	1:1000
Other Accession	Q8R4K2; Q1RMT8; NP_001107654.1; NP_057207.2
Predicted	B, M
Isotype	Rabbit Ig
Calculated MW	51530
Antigen Region	25-52
Antigen Source	HUMAN
Target/Specificity	This IRAK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-52 amino acids from the N-terminal region of human IRAK4.
NCBI Accession	NP_001107654.1; NP_001138728.1; NP_001138729.1; NP_001138730.1; NP_057207.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 10/2/2025

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