STAT2 Antibody (N-term)

Synthetic Peptide

The protein encoded by this gene is a member of the STAT
protein family. In response to cytokines and growth factors, STAT
family members are phosphorylated by the receptor associated
kinases, and then form homo- or heterodimers that translocate to
the cell nucleus where they act as transcription activators. In
response to interferon (IFN), this protein forms a complex with
STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in
which this protein acts as a transactivator, but lacks the ability
to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP)
has been shown to interact specifically with this protein, which is
thought to be involved in the process of blocking IFN-alpha
response by adenovirus. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].

Polyclonal

6773

Affinity Purified Rabbit Polyclonal Antibody (Pab)

STAT2 Antibody (N-term) (Cat. #AP13749a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the STAT2 antibody detected the STAT2 protein (arrow).

1:1000

IHC-P

O02799; NP_005410.1; NP_938146.1

Rabbit Ig

186-215

This STAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the N-terminal region of human STAT2.