Manufacturer |
Abcepta
|
Category |
|
Type |
Antibody Primary |
Specific against |
other |
Isotype |
Ig |
Format |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Applications |
WB, IHC-P |
Amount |
400 ul |
Host |
Rabbit |
Item no. |
ABC-AP13749a |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Primary Accession |
P52630 |
Antigen Type |
Synthetic Peptide |
Application |
IHC-P, WB |
Bio Background |
The protein encoded by this gene is a member of the STATprotein family. In response to cytokines and growth factors, STATfamily members are phosphorylated by the receptor associatedkinases, and then form homo- or heterodimers that translocate tothe cell nucleus where they act as transcription activators. Inresponse to interferon (IFN), this protein forms a complex withSTAT1 and IFN regulatory factor family protein p48 (ISGF3G), inwhich this protein acts as a transactivator, but lacks the abilityto bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP)has been shown to interact specifically with this protein, which isthought to be involved in the process of blocking IFN-alpharesponse by adenovirus. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq]. |
Bio References |
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Lou, Y.J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(3):255-258(2010)Rosas-Murrieta, N.H., et al. Virol. J. 7, 263 (2010) : |
Clonality |
Polyclonal |
Clone/Animal Names |
RB33744 |
Gene ID |
6773 |
Gene Name |
STAT2 |
Subtitle |
Affinity Purified Rabbit Polyclonal Antibody (Pab) |
Reactivity |
H |
Legend image 1 |
STAT2 Antibody (N-term) (Cat. #AP13749a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the STAT2 antibody detected the STAT2 protein (arrow). |
Type image 1 |
WB |
Dilution image 1 |
1:1000 |
Legend image 2 |
STAT2 Antibody (N-term) (Cat. #AP13749a)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STAT2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
Type image 2 |
IHC-P |
Dilution image 2 |
1:10~50 |
Other Accession |
O02799; NP_005410.1; NP_938146.1 |
Predicted |
Pig |
Isotype |
Rabbit Ig |
Calculated MW |
97916 |
Antigen Region |
186-215 |
Antigen Source |
HUMAN |
Target/Specificity |
This STAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the N-terminal region of human STAT2. |
NCBI Accession |
NP_005410.1; NP_938146.1 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.