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PPL Antibody (C-term)

ArtNr ABC-AP14171b-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010):
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010):
Pyle, A.L., et al. Cardiovasc. Pathol. 19 (2), E13-E20 (2010):
Huang, Y., et al. Arch. Dermatol. Res. 301(10):703-709(2009)
Boczonadi, V., et al. Exp. Cell Res. 313(16):3579-3591(2007)
NCBI NP_002696.3
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Periplakin,190 kDa paraneoplastic pemphigus antigen,195 kDa cornified envelope precursor protein,PPL,KIAA0568
Similar products PPL, KIAA0568, Periplakin, 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein
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Manufacturer - Category
Primary Antibodies; Immunology; Signal Transduction; Mitochondrion
Manufacturer - Targets
This PPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1301-1330 amino acids from the C-terminal region of human PPL.
Bio Background
The protein encoded by this gene is a component ofdesmosomes and of the epidermal cornified envelope inkeratinocytes. The N-terminal domain of this protein interacts withthe plasma membrane and its C-terminus interacts with intermediatefilaments. Through its rod domain, this protein forms complexeswith envoplakin. This protein may serve as a link between thecornified envelope and desmosomes as well as intermediatefilaments. AKT1/PKB, a protein kinase mediating a variety of cellgrowth and survival signaling processes, is reported to interactwith this protein, suggesting a possible role for this protein as alocalization signal in AKT1-mediated signaling. [provided byRefSeq].
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB18945
Gene Name
PPL
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
204747
Antigen Source
HUMAN
Antigen Region
1301-1330
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
IHC-P: 1:10~50
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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