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PPL Antibody (C-term)

PPL Antibody (C-term)

ArtNr	ABC-AP14171b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PPL, KIAA0568, Periplakin, 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein
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Primary Accession	O60437
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq].
Bio References	Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Pyle, A.L., et al. Cardiovasc. Pathol. 19 (2), E13-E20 (2010) : Huang, Y., et al. Arch. Dermatol. Res. 301(10):703-709(2009) Boczonadi, V., et al. Exp. Cell Res. 313(16):3579-3591(2007)
Clonality	Polyclonal
Clone/Animal Names	RB18945
Gene ID	5493
Gene Name	PPL
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	PPL Antibody (C-term) (Cat. #AP14171b) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PPL antibody detected the PPL protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	PPL Antibody (C-term) (Cat. #AP14171b)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PPL Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_002696.3
Isotype	Rabbit Ig
Calculated MW	204747
Antigen Region	1301-1330
Antigen Source	HUMAN
Target/Specificity	This PPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1301-1330 amino acids from the C-terminal region of human PPL.
NCBI Accession	NP_002696.3

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ABC-AP14171b-ev-datasheet.pdf

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Menge: 80 ul

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Lieferung vsl. bis 04.09.2025

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