TRAF4 Antibody (C-term)

Synthetic Peptide

This gene encodes a member of the TNF receptor associated
factor (TRAF) family. TRAF proteins are associated with, and
mediate signal transduction from members of the TNF receptor
superfamily. The encoded protein has been shown to interact with
neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR
induced cell death and NF-kappa B activation. This protein has been
found to bind to p47phox, a cytosolic regulatory factor included in
a multi-protein complex known as NAD(P)H oxidase. This protein
thus, is thought to be involved in the oxidative activation of
MAPK8/JNK. Alternatively spliced transcript variants have been
observed but the full-length nature of only one has been
determined.

Polyclonal

9618

Affinity Purified Rabbit Polyclonal Antibody (Pab)

TRAF4 Antibody (C-term) (Cat. #AP16059b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TRAF4 antibody detected the TRAF4 protein (arrow).

1:1000

M

53543

HUMAN

NP_004286.2