LEP Antibody (N-term)

Primary Antibodies; Cardiovascular; Metabolism; Neuroscience; Signal Transduction; Jak-STAT signaling KEGG

This gene encodes a protein that is secreted by whiteadipocytes, and which plays a major role in the regulation of bodyweight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit foodintake and/or regulate energy expenditure to maintain constancy ofthe adipose mass. This protein also has several endocrinefunctions, and is involved in the regulation of immune andinflammatory responses, hematopoiesis, angiogenesis and woundhealing. Mutations in this gene and/or its regulatory regions causesevere obesity, and morbid obesity with hypogonadism. This gene hasalso been linked to type 2 diabetes mellitus development. [providedby RefSeq].

RB36463

Affinity Purified Rabbit Polyclonal Antibody (Pab)

M

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide