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PTPN5 Antibody (N-term)

PTPN5 Antibody (N-term)

ArtNr	ABC-AP17036a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Kurup, P., et al. J. Neurosci. 30(17):5948-5957(2010) Rose, J. Phd, et al. Mol. Med. (2010) In press: Korff, S., et al. BMC Cancer 8, 329 (2008): Eswaran, J., et al. Biochem. J. 395(3):483-491(2006) Nguyen, T.H., et al. J. Biol. Chem. 277(27):24274-24279(2002)
NCBI	NP_001035059.1,NP_001265165.1,NP_001265167.1,NP_001265168.1,NP_008837.1,NP_116170.3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tyrosine-protein phosphatase non-receptor type 5,Neural-specific protein-tyrosine phosphatase,Striatum-enriched protein-tyrosine phosphatase,STEP,PTPN5
Similar products	PTPN5, Tyrosine-protein phosphatase non-receptor type 5, Neural-specific protein-tyrosine phosphatase, Striatum-enriched protein-tyrosine phosphatase, STEP
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Manufacturer - Category	Primary Antibodies; Neuroscience; Signal Transduction; Catalog Updated
Manufacturer - Targets	This PTPN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PTPN5.
Bio Background	STEP (Protein-tyrosine phosphatase striatum-enriched) is a neural-specific protein-tyrosine phosphatase. It is also known as PTPN5 (tyrosine-protein phosphatase, non-receptor type 5). STEP immunoreactive areas are most intense in the regions of the CNS receiving a dopaminergic input (e.g. striatum, basal ganglia). STEP is part of the NMDA receptor (R) complex and inhibits NMDAR single-channel activity and NMDAR-mediated synaptic current. Phosphorylation of STEP, via D1 and PKA activation by dopamine, decreases the activity of STEP by reducing its affinity for substrate.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36818
Gene Name	PTPN5
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	63538
Antigen Source	HUMAN
Antigen Region	1-30
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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