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PTPN5 Antibody (N-term)

PTPN5 Antibody (N-term)

Item no.	ABC-AP17036a
Manufacturer	Abcepta
Amount	400 ul
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Kurup, P., et al. J. Neurosci. 30(17):5948-5957(2010) Rose, J. Phd, et al. Mol. Med. (2010) In press: Korff, S., et al. BMC Cancer 8, 329 (2008): Eswaran, J., et al. Biochem. J. 395(3):483-491(2006) Nguyen, T.H., et al. J. Biol. Chem. 277(27):24274-24279(2002)
NCBI	NP_001035059.1,NP_001265165.1,NP_001265167.1,NP_001265168.1,NP_008837.1,NP_116170.3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tyrosine-protein phosphatase non-receptor type 5,Neural-specific protein-tyrosine phosphatase,Striatum-enriched protein-tyrosine phosphatase,STEP,PTPN5
Similar products	PTPN5, Tyrosine-protein phosphatase non-receptor type 5, Neural-specific protein-tyrosine phosphatase, Striatum-enriched protein-tyrosine phosphatase, STEP
Available
Manufacturer - Category	Primary Antibodies; Neuroscience; Signal Transduction; Catalog Updated
Manufacturer - Targets	This PTPN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PTPN5.
Bio Background	STEP (Protein-tyrosine phosphatase striatum-enriched) is a neural-specific protein-tyrosine phosphatase. It is also known as PTPN5 (tyrosine-protein phosphatase, non-receptor type 5). STEP immunoreactive areas are most intense in the regions of the CNS receiving a dopaminergic input (e.g. striatum, basal ganglia). STEP is part of the NMDA receptor (R) complex and inhibits NMDAR single-channel activity and NMDAR-mediated synaptic current. Phosphorylation of STEP, via D1 and PKA activation by dopamine, decreases the activity of STEP by reducing its affinity for substrate.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36818
Gene Name	PTPN5
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	63538
Antigen Source	HUMAN
Antigen Region	1-30
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 3/5/2026

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