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TPP1 Antibody (N-term)

TPP1 Antibody (N-term)

ArtNr	ABC-AP17047a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Souweidane, M.M., et al. J Neurosurg Pediatr 6(2):115-122(2010) Walus, M., et al. Hum. Mutat. 31(6):710-721(2010) Latrick, C.M., et al. EMBO J. 29(5):924-933(2010) Kuizon, S., et al. PLoS ONE 5 (8), E11929 (2010): Goldberg-Stern, H., et al. Pediatr. Neurol. 41(4):297-300(2009)
NCBI	NP_000382.3
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tripeptidyl-peptidase 1,TPP-1,Cell growth-inhibiting gene 1 protein,Lysosomal pepstatin-insensitive protease,LPIC,Tripeptidyl aminopeptidase,Tripeptidyl-peptidase I,TPP-I,TPP1,CLN2
Similar products	TPP1, CLN2, Tripeptidyl-peptidase 1, Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, LPIC, TPP-1, TPP-I
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Manufacturer - Category	Primary Antibodies; Cell Biology; Neuroscience; Lysosome
Manufacturer - Targets	This TPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human TPP1.
Bio Background	This gene encodes a member of the sedolisin family ofserine proteases. The protease functions in the lysosome to cleaveN-terminal tripeptides from substrates, and has weakerendopeptidase activity. It is synthesized as acatalytically-inactive enzyme which is activated andauto-proteolyzed upon acidification. Mutations in this gene resultin late-infantile neuronal ceroid lipofuscinosis, which isassociated with the failure to degrade specific neuropeptides and asubunit of ATP synthase in the lysosome.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36843
Gene Name	TPP1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	Pr
Calculated Molecular Weight	61248
Antigen Source	HUMAN
Antigen Region	6-34
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 05.03.2026

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