Comparison

TPP1 Antibody (N-term)

Item no. ABC-AP17047a
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Souweidane, M.M., et al. J Neurosurg Pediatr 6(2):115-122(2010)
Walus, M., et al. Hum. Mutat. 31(6):710-721(2010)
Latrick, C.M., et al. EMBO J. 29(5):924-933(2010)
Kuizon, S., et al. PLoS ONE 5 (8), E11929 (2010):
Goldberg-Stern, H., et al. Pediatr. Neurol. 41(4):297-300(2009)
NCBI NP_000382.3
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tripeptidyl-peptidase 1,TPP-1,Cell growth-inhibiting gene 1 protein,Lysosomal pepstatin-insensitive protease,LPIC,Tripeptidyl aminopeptidase,Tripeptidyl-peptidase I,TPP-I,TPP1,CLN2
Similar products TPP1, CLN2, Tripeptidyl-peptidase 1, Cell growth-inhibiting gene 1 protein, Lysosomal pepstatin-insensitive protease, Tripeptidyl aminopeptidase, Tripeptidyl-peptidase I, LPIC, TPP-1, TPP-I
Available
Manufacturer - Category
Primary Antibodies; Cell Biology; Neuroscience; Lysosome
Manufacturer - Targets
This TPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human TPP1.
Bio Background
This gene encodes a member of the sedolisin family ofserine proteases. The protease functions in the lysosome to cleaveN-terminal tripeptides from substrates, and has weakerendopeptidase activity. It is synthesized as acatalytically-inactive enzyme which is activated andauto-proteolyzed upon acidification. Mutations in this gene resultin late-infantile neuronal ceroid lipofuscinosis, which isassociated with the failure to degrade specific neuropeptides and asubunit of ATP synthase in the lysosome.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB36843
Gene Name
TPP1
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
Pr
Calculated Molecular Weight
61248
Antigen Source
HUMAN
Antigen Region
6-34
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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