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TTK Antibody (N-term)

TTK Antibody (N-term)

ArtNr	ABC-AP17197a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Mesothelioma Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Cui, Y., et al. J. Biol. Chem. 285(43):32988-32998(2010) Maciejowski, J., et al. J. Cell Biol. 190(1):89-100(2010) Santaguida, S., et al. J. Cell Biol. 190(1):73-87(2010) Hewitt, L., et al. J. Cell Biol. 190(1):25-34(2010) Lan, W., et al. J. Cell Biol. 190(1):21-24(2010)
NCBI	NP_001160163.1,NP_003309.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dual specificity protein kinase TTK,Phosphotyrosine picked threonine-protein kinase,PYT,TTK,MPS1,MPS1L1
Similar products	TTK, MPS1, MPS1L1, Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT
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Manufacturer - Category	Primary Antibodies; Cell Biology; Anti-Kinome Antibodies
Manufacturer - Targets	This TTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human TTK.
Bio Background	This gene encodes a dual specificity protein kinase withthe ability to phosphorylate tyrosine, serine and threonine.Associated with cell proliferation, this protein is essential forchromosome alignment at the centromere during mitosis and isrequired for centrosome duplication. It has been found to be acritical mitotic checkpoint protein for accurate segregation ofchromosomes during mitosis. Tumorigenesis may occur when thisprotein fails to degrade and produces excess centrosomes resultingin aberrant mitotic spindles. Alternative splicing results inmultiple transcript variants.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36754
Gene Name	TTK
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	Pr
Calculated Molecular Weight	97072
Antigen Source	HUMAN
Antigen Region	6-35
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 05.03.2026

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