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DRAM Antibody (C-term)

DRAM Antibody (C-term)

ArtNr	ABC-AP1825c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DRAM, DRAM1, Damage-regulated autophagy modulator, DNA damage-regulated autophagy modulator protein 1
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Primary Accession	Q8N682
Antigen Type	Synthetic Peptide
Application	IHC-P
Bio Background	DRAM is regulated as part of the p53 tumor suppressor pathway. It is a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this protein is associated with various tumors.
Bio References	Kerley-Hamilton, J.S., Biochim. Biophys. Acta 1769 (4), 209-219 (2007) Crighton, D., Autophagy 3 (1), 72-74 (2007) Crighton, D., Cell 126 (1), 121-134 (2006) Green, D.R., Cell 126 (1), 30-32 (2006)
Clonality	Polyclonal
Clone/Animal Names	RB12480
Gene ID	55332
Gene Name	DRAM1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with DRAM Antibody (C-term) (Cat.#AP1825c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 1	IHC-P
Dilution image 1	1:10~50
Isotype	Rabbit Ig
Calculated MW	26253
Antigen Region	176-206
Antigen Source	HUMAN
Target/Specificity	This DRAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176~206 amino acids from the C-terminal region of human DRAM.
NCBI Accession	NP_060840.2

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ABC-AP1825c-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 03.07.2025

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