« Back
Home /
DRAM Antibody (C-term)

DRAM Antibody (C-term)

Item no.	ABC-AP1825c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DRAM, DRAM1, Damage-regulated autophagy modulator, DNA damage-regulated autophagy modulator protein 1
Available
Primary Accession	Q8N682
Antigen Type	Synthetic Peptide
Application	IHC-P
Bio Background	DRAM is regulated as part of the p53 tumor suppressor pathway. It is a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this protein is associated with various tumors.
Bio References	Kerley-Hamilton, J.S., Biochim. Biophys. Acta 1769 (4), 209-219 (2007) Crighton, D., Autophagy 3 (1), 72-74 (2007) Crighton, D., Cell 126 (1), 121-134 (2006) Green, D.R., Cell 126 (1), 30-32 (2006)
Clonality	Polyclonal
Clone/Animal Names	RB12480
Gene ID	55332
Gene Name	DRAM1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with DRAM Antibody (C-term) (Cat.#AP1825c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 1	IHC-P
Dilution image 1	1:10~50
Isotype	Rabbit Ig
Calculated MW	26253
Antigen Region	176-206
Antigen Source	HUMAN
Target/Specificity	This DRAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176~206 amino acids from the C-terminal region of human DRAM.
NCBI Accession	NP_060840.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-AP1825c-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 400 ul

available

Delivery expected until 7/3/2025

Express Delivery: Save 15 days

Compare

Add to wishlist

Recommend by mail