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Phospho-EP300(S89) Antibody

Phospho-EP300(S89) Antibody

ArtNr	ABC-AP3197a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Immunohistochemistry Primary Antibodies Dot Blot
Typ	Antibody Polyclonal
Applikationen	IHC-P, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Finlan, L., et al., J. Biol. Chem. 279(47):49395-49405 (2004). Dornan, D., et al., Mol. Cell. Biol. 24(22):10083-10098 (2004). Jin, Y.H., et al., J. Biol. Chem. 279(28):29409-29417 (2004). Kung, A.L., et al., Cancer Cell 6(1):33-43 (2004). Chen, J., et al., Cell. Mol. Life Sci. 61(13):1675-1683 (2004).
NCBI	NP_001420.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone acetyltransferase p300,p300 HAT,E1A-associated protein p300,EP300,P300
Similar products	EP300, P300, Histone acetyltransferase p300, E1A-associated protein p300, p300 HAT
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Metabolism; Signal Transduction; Phospho Antibodies; Anti-Wnt-Pathway (plus Lgr5) Antibodies; Viral process; Host-virus interaction; Jak-STAT signaling KEGG
Manufacturer - Targets	This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S89 of human EP300.
Bio Background	EP3 encodes the adenovirus E1A-associated cellular p3 transcriptional co-activator protein. p3 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP3 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP3 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB7876
Gene Name	EP300 {ECO:0000303\|PubMed:15706485, ECO:0000312\|HGNC:HGNC:3373}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M
Calculated Molecular Weight	264161
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IHC-P: 1:50~100 DB: 1:500
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 01.01.2026

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