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Phospho-EP300(S89) Antibody

Phospho-EP300(S89) Antibody

Item no.	ABC-AP3197a
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Immunohistochemistry Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	IHC-P, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Finlan, L., et al., J. Biol. Chem. 279(47):49395-49405 (2004). Dornan, D., et al., Mol. Cell. Biol. 24(22):10083-10098 (2004). Jin, Y.H., et al., J. Biol. Chem. 279(28):29409-29417 (2004). Kung, A.L., et al., Cancer Cell 6(1):33-43 (2004). Chen, J., et al., Cell. Mol. Life Sci. 61(13):1675-1683 (2004).
NCBI	NP_001420.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Histone acetyltransferase p300,p300 HAT,E1A-associated protein p300,EP300,P300
Similar products	EP300, P300, Histone acetyltransferase p300, E1A-associated protein p300, p300 HAT
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Metabolism; Signal Transduction; Phospho Antibodies; Anti-Wnt-Pathway (plus Lgr5) Antibodies; Viral process; Host-virus interaction; Jak-STAT signaling KEGG
Manufacturer - Targets	This EP300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S89 of human EP300.
Bio Background	EP3 encodes the adenovirus E1A-associated cellular p3 transcriptional co-activator protein. p3 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP3 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP3 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB7876
Gene Name	EP300 {ECO:0000303\|PubMed:15706485, ECO:0000312\|HGNC:HGNC:3373}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M
Calculated Molecular Weight	264161
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IHC-P: 1:50~100 DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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