Phospho-TBK(S172) Antibody

Primary Antibodies; Antibody Collections; Signal Transduction; Phospho Antibodies; Antiviral defense; Host-virus interaction; Immunity; Innate immunity; RIG-l-like Receptor; Toll receptor signaling; Toll-Like receptor signaling; SARS druggable targets; SARS CoV2 PPIs; Infection

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.

RB16573

Pepide Affinity Purified Rabbit Polyclonal Antibody (Pab)

M, X

HUMAN

WB: 1:1000
DB: 1:500