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Phospho-TBK(S172) Antibody

Phospho-TBK(S172) Antibody

Item no.	ABC-AP3627a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Western Blot Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	WB, Dot
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Deng,W., J. Biol. Chem. 283 (51), 35590-35597 (2008) Chessler,A.D., J. Immunol. 181 (11), 7917-7924 (2008) Soulat,D., EMBO J. 27 (15), 2135-2146 (2008)
NCBI	NP_037386.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase TBK1,NF-kappa-B-activating kinase,T2K,TANK-binding kinase 1,TBK1,NAK
Similar products	NAK, TBK1, Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, NF-kappa-B-activating kinase
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Signal Transduction; Phospho Antibodies; Antiviral defense; Host-virus interaction; Immunity; Innate immunity; RIG-l-like Receptor; Toll receptor signaling; Toll-Like receptor signaling; SARS druggable targets; SARS CoV2 PPIs; Infection
Manufacturer - Targets	This TBK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S172 of human TBK.
Bio Background	The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. TKB is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB16573
Gene Name	TBK1 {ECO:0000303\|PubMed:10581243, ECO:0000312\|HGNC:HGNC:11584}
Subtitle	Pepide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	M, X
Calculated Molecular Weight	83642
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 DB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 1/1/2026

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