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IKZF3 Antibody (Center)

ArtNr ABC-AP5656C-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Billot, K., et al. Leuk. Res. 34(3):289-293(2010)
Hirschfield, G.M., et al. N. Engl. J. Med. 360(24):2544-2555(2009)
Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)
Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
NCBI NP_001244337.1,NP_001244338.1,NP_001244339.1,NP_001244340.1,NP_001244341.1,NP_001244342.1,NP_001244343.1,NP_036613.2,NP_899051.1,NP_899052.1,NP_899053.1,NP_899054.1,NP_899055.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Zinc finger protein Aiolos,Ikaros family zinc finger protein 3,IKZF3,ZNFN1A3
Similar products IKZF3, ZNFN1A3, Ikaros family zinc finger protein 3, Zinc finger protein Aiolos
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Manufacturer - Category
Primary Antibodies; B-cell activation
Manufacturer - Targets
This IKZF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-103 amino acids from the Central region of human IKZF3.
Bio Background
This gene encodes a member of the Ikaros family ofzinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factorsinvolved in the regulation of lymphocyte development. This geneproduct is a transcription factor that is important in theregulation of B lymphocyte proliferation and differentiation. BothIkaros and Aiolos can participate in chromatin remodeling.Regulation of gene expression in B lymphocytes by Aiolos is complexas it appears to require the sequential formation of Ikaroshomodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Atleast six alternative transcripts encoding different isoforms havebeen described.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB30017
Gene Name
IKZF3
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H, M
Predicted Reactivity
B
Calculated Molecular Weight
58023
Antigen Source
HUMAN
Antigen Region
76-103
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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