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IKZF3 Antibody (Center)

IKZF3 Antibody (Center)

Item no.	ABC-AP5656C-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Neuroscience Neural Epigenetics Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Billot, K., et al. Leuk. Res. 34(3):289-293(2010) Hirschfield, G.M., et al. N. Engl. J. Med. 360(24):2544-2555(2009) Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009) Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)
NCBI	NP_001244337.1,NP_001244338.1,NP_001244339.1,NP_001244340.1,NP_001244341.1,NP_001244342.1,NP_001244343.1,NP_036613.2,NP_899051.1,NP_899052.1,NP_899053.1,NP_899054.1,NP_899055.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Zinc finger protein Aiolos,Ikaros family zinc finger protein 3,IKZF3,ZNFN1A3
Similar products	IKZF3, ZNFN1A3, Ikaros family zinc finger protein 3, Zinc finger protein Aiolos
Available
Manufacturer - Category	Primary Antibodies; B-cell activation
Manufacturer - Targets	This IKZF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-103 amino acids from the Central region of human IKZF3.
Bio Background	This gene encodes a member of the Ikaros family ofzinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factorsinvolved in the regulation of lymphocyte development. This geneproduct is a transcription factor that is important in theregulation of B lymphocyte proliferation and differentiation. BothIkaros and Aiolos can participate in chromatin remodeling.Regulation of gene expression in B lymphocytes by Aiolos is complexas it appears to require the sequential formation of Ikaroshomodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Atleast six alternative transcripts encoding different isoforms havebeen described.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB30017
Gene Name	IKZF3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	B
Calculated Molecular Weight	58023
Antigen Source	HUMAN
Antigen Region	76-103
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 3/5/2026

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