GRB2 Antibody (Y209)

ArtNr	ABC-AP6283a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Kondo,A., J. Biol. Chem. 283 (3), 1428-1436 (2008) Morimatsu,M., Proc. Natl. Acad. Sci. U.S.A. 104 (46), 18013-18018 (2007) Martinez,N., Cell. Signal. 19 (11), 2277-2285 (2007)
NCBI	NP_002077.1,NP_987102.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Growth factor receptor-bound protein 2,Adapter protein GRB2,Protein Ash,SH2/SH3 adapter GRB2,GRB2,ASH
Similar products	GRB2, ASH, Growth factor receptor-bound protein 2, Adapter protein GRB2, SH2/SH3 adapter GRB2, Protein Ash
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Manufacturer - Category	Crown Antibodies; Primary Antibodies; Cancer; Signal Transduction; Viral process; Host-virus interaction; B cell receptor signaling; T cell activation; T cell receptor signaling; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling; Jak-STAT signaling KEGG
Manufacturer - Targets	This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
Bio Background	GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB11305-11306
Gene Name	GRB2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	X, C, M, Rat
Calculated Molecular Weight	25206
Antigen Source	HUMAN
Antigen Region	187-216
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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