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APP Antibody (N-term)

APP Antibody (N-term)

ArtNr	ABC-AP6306A
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Adenocarcinoma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, FC, IHC-P
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Borroni, B., et al., Arch. Neurol. 60(12):1740-1744 (2003). Lleo, A., et al., J. Biol. Chem. 278(48):47370-47375 (2003). Zhou, Y., et al., Science 302(5648):1215-1217 (2003). Murakami, K., et al., J. Biol. Chem. 278(46):46179-46187 (2003). Kim, J.Y., et al., Biochem. Biophys. Res. Commun. 310(3):904-909 (2003).
NCBI	NP_000475.1,NP_001129488.1,NP_001129601.1,NP_001129602.1,NP_001129603.1,NP_001191230.1,NP_001191231.1,NP_001191232.1,NP_958816.1,NP_958817.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	APP, A4, AD1, Amyloid beta A4 protein, ABPP, APPI, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, N-APP, Soluble APP-alpha, Soluble APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, CVAP, Beta-APP40, Beta-amyloid protein 40, PN-II, C31, C80, C83, AICD-50, AICD-57, AICD-59, AID(50), AID(57), AID(59), Amyloid intracellular domain 50, Amyloid intracellular domain 57, Amyloid intracellular domain 59, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), S-APP-alpha
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Manufacturer - Category	Primary Antibodies; Neuroscience; Inflammasome
Manufacturer - Targets	This APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-61 amino acids from the N-terminal region of human APP.
Bio Background	APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP6 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB5012
Gene Name	APP
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Predicted Reactivity	Pr
Calculated Molecular Weight	86943
Antigen Source	HUMAN
Antigen Region	29-61
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:2000 IHC-P: 1:10~50 FC: 1:10~50
Antigen Type	Synthetic Peptide
Manufacturer - Alias	Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50), C31, APP, A4, AD1
Manufacturer - Similar	Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50), C31, APP, A4, AD1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 01.01.2026

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