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ABCG1 Antibody (Center)

ABCG1 Antibody (Center)

ArtNr	ABC-AP6529c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ABCG1, ABC8, ATP-binding cassette sub-family G member 1, ATP-binding cassette transporter 8, White protein homolog, WHT1
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Primary Accession	P45844
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types.
Bio References	Furuyama, S., J. Atheroscler. Thromb. 16 (3), 194-200 (2009) Stefulj, J., Circ. Res. 104 (5), 600-608 (2009) Mauerer, R., Exp. Mol. Med. 41 (2), 126-132 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB19679
Gene ID	9619
Gene Name	ABCG1 (HGNC:73)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-ABCG1 Antibody (Center) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 76 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with ABCG1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	ABCG1 Antibody (Center) (Cat.#AP6529c) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	75592
Antigen Region	359-387
Antigen Source	HUMAN
Target/Specificity	This ABCG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-387 amino acids from the Central region of human ABCG1.
NCBI Accession	NP_004906.3; NP_058198.2; NP_997057.1; NP_997510.1; NP_997511.1; NP_997512.1

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ABC-AP6529c-datasheet.pdf

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Menge: 400 ul

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