Vergleich

Aurora-C Antibody (C-term)

ArtNr ABC-AP7000c-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen WB
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products AURKC, AIE2, AIK3, AIRK3, ARK3, STK13, Aurora kinase C, Aurora 3, Aurora/IPL1-related kinase 3, Aurora/IPL1/Eg2 protein 2, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C, ARK-3, Aurora-related kinase 3
Lieferbar
Primary Accession
Q9UQB9
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Bio References
Kimura, M., et al., J. Biol. Chem. 274(11):7334-7340 (1999).
Tseng, T.C., et al., DNA Cell Biol. 17(10):823-833 (1998).
Bernard, M., et al., Genomics 53(3):406-409 (1998).
Clonality
Polyclonal
Clone/Animal Names
RB6820
Gene ID
6795
Gene Name
AURKC
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
The anti-Aurora-C C-term Pab (Cat. #AP7000c) is used in Western blot to detect Aurora C in A375 cell lysate.
Type image 1
WB
Dilution image 1
1:1000
Isotype
Rabbit Ig
Calculated MW
35591
Antigen Region
220-250
Antigen Source
HUMAN
Target/Specificity
This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from the C-terminal region of human Aurora-C.
NCBI Accession
NP_001015878.1; NP_001015879.1; NP_003151.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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