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Aurora-C Antibody (C-term)

Aurora-C Antibody (C-term)

Item no.	ABC-AP7000c-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	AURKC, AIE2, AIK3, AIRK3, ARK3, STK13, Aurora kinase C, Aurora 3, Aurora/IPL1-related kinase 3, Aurora/IPL1/Eg2 protein 2, Serine/threonine-protein kinase 13, Serine/threonine-protein kinase aurora-C, ARK-3, Aurora-related kinase 3
Available
Primary Accession	Q9UQB9
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Bio References	Kimura, M., et al., J. Biol. Chem. 274(11):7334-7340 (1999). Tseng, T.C., et al., DNA Cell Biol. 17(10):823-833 (1998). Bernard, M., et al., Genomics 53(3):406-409 (1998).
Clonality	Polyclonal
Clone/Animal Names	RB6820
Gene ID	6795
Gene Name	AURKC
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	The anti-Aurora-C C-term Pab (Cat. #AP7000c) is used in Western blot to detect Aurora C in A375 cell lysate.
Type image 1	WB
Dilution image 1	1:1000
Isotype	Rabbit Ig
Calculated MW	35591
Antigen Region	220-250
Antigen Source	HUMAN
Target/Specificity	This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-250 amino acids from the C-terminal region of human Aurora-C.
NCBI Accession	NP_001015878.1; NP_001015879.1; NP_003151.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 10/2/2025

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