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Aromatase (CYP19A1) Antibody (Center)

ArtNr ABC-AP7293c
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products Aromatase, CYP19A1, ARO1, CYAR, CYP19, Cytochrome P450 19A1, CYPXIX, Estrogen synthase, Cytochrome P-450AROM
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Primary Accession
P11511
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.
Bio References
Ikeda, S., Am. J. Gastroenterol. 103 (6), 1476-1487 (2008)
Dos Santos, (er) DNA Cell Biol. (2008) In press
Nelson, Pharmacogenetics 14 (1), 1-18 (2004)
Clonality
Polyclonal
Clone/Animal Names
RB14619
Gene ID
1588
Gene Name
CYP19A1 {ECO:0000303|PubMed:24705274, ECO:0000312|HGNC:HGNC:2594}
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of anti-CYP19A1(Center) Pab (Cat.#AP7293c) in HL60 cell line lysates (35ug/lane). CYP19A1(arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Other Accession
Q29605
Predicted
Rb
Isotype
Rabbit Ig
Calculated MW
57883
Antigen Region
221-253
Antigen Source
HUMAN
Target/Specificity
This Aromatase (CYP19A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-253 amino acids from the Central region of human Aromatase (CYP19A1).
NCBI Accession
NP_000094.2; NP_112503.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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