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MYCN Antibody (C-term)

ArtNr ABC-AP7395b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MYCN, NMYC, bHLHe37, N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, BHLHE37
Lieferbar
Primary Accession
P04198
Antigen Type
Synthetic Peptide
Application
WB, IHC-P
Bio Background
MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.
Bio References
Combaret, V., Pediatr Blood Cancer 53 (3), 329-331 (2009)
Alvarez-Rodriguez, R., J. Cell. Sci. 122 (PT 5), 595-599 (2009)
Jacobs, J.F., BMC Cancer 9, 239 (2009)
Clonality
Polyclonal
Clone/Animal Names
RB18771
Gene ID
4613
Gene Name
MYCN
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Anti-MYCN Antibody (C-term) at 1:1000 dilution + CCRF-CEM whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 50 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded H.brain tissue reacted with MYCN Antibody (C-term) (Cat#AP7395b).
Type image 2
IHC-P
Dilution image 2
1:100
Other Accession
Q63379; P03966
Predicted
M, Rat
Isotype
Rabbit Ig
Calculated MW
49561
Antigen Region
322-351
Antigen Source
HUMAN
Target/Specificity
This MYCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human MYCN.
NCBI Accession
NP_005369.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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