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GDF6 Antibody (C-term)

GDF6 Antibody (C-term)

ArtNr	ABC-AP7483B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	GDF6, GDF16, Growth/differentiation factor 6, Growth/differentiation factor 16, BMP13, BMP-13, GDF-6, Bone morphogenetic protein 13
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Primary Accession	Q6KF10
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	GDF6 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this protein result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.
Bio References	Tassabehji M., Fang Z.M.Hum. Mutat. 29:1017-1027(2008)
Clonality	Polyclonal
Clone/Animal Names	RB15615
Gene ID	392255
Gene Name	GDF6
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of GDF6 antibody (C-term) (Cat.#AP7483b) in mouse kidney tissue lysates (35ug/lane). GDF6 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human brain tissue reacted with GDF6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	Flow cytometric analysis of 293 cells using GDF6 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	Q6HA10; P43028; P55106
Predicted	B, Rat
Isotype	Rabbit Ig
Calculated MW	50662
Antigen Region	326-353
Antigen Source	HUMAN
Target/Specificity	This GDF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-353 amino acids from the C-terminal region of human GDF6.
NCBI Accession	NP_001001557.1

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ABC-AP7483B-datasheet.pdf

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Menge: 400 ul

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