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MAPK11 Antibody (C-term)

MAPK11 Antibody (C-term)

ArtNr	ABC-AP7509B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, MAPK11, PRKM11, SAPK2, SAPK2B, Stress-activated protein kinase 2b, p38-2, MAP kinase 11, MAPK 11, MAP kinase p38 beta, p38b, SAPK2b
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Primary Accession	Q15759
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
Bio References	Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Dunham, I., et al., Nature 402(6761):489-495 (1999). Enslen, H., et al., J. Biol. Chem. 273(3):1741-1748 (1998). Kumar, S., et al., Biochem. Biophys. Res. Commun. 235(3):533-538 (1997). Goedert, M., et al., EMBO J. 16(12):3563-3571 (1997).
Clonality	Polyclonal
Clone/Animal Names	RB6825
Gene ID	5600
Gene Name	MAPK11
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of anti-P38beta Antibody (C-term) (Cat. #AP7509b) in mouse heart tissue lysates (35ug/lane). P38beta (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	P38beta Antibody (C-term) (Cat. #AP7509b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P38beta antibody detected the P38beta protein (arrow).
Type image 2	WB
Dilution image 2	1:1000
Other Accession	Q2XNF2
Isotype	Rabbit Ig
Calculated MW	41357
Antigen Region	334-359
Antigen Source	HUMAN
Target/Specificity	This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-359 amino acids from the C-terminal region of human MAPK11.
NCBI Accession	NP_002742.3

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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