Vergleich

ALK Antibody (C-term)

ArtNr ABC-AP7600b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products ALK, ALK tyrosine kinase receptor, CD246, Anaplastic lymphoma kinase
Lieferbar
Primary Accession
Q9UM73
Antigen Type
Synthetic Peptide
Application
IHC-P
Bio Background
ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2; 5)(p23; q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
Bio References
Morris, S.W., et al., Oncogene 14(18):2175-2188 (1997).
Iwahara, T., et al., Oncogene 14(4):439-449 (1997).
Morris, S.W., et al., Science 263(5151):1281-1284 (1994).
Morris, S.W., et al., Oncogene 15, 2883-2883 (1997).
Clonality
Polyclonal
Clone/Animal Names
RB1513-1514
Gene ID
238
Gene Name
ALK (HGNC:427)
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 1
IHC-P
Dilution image 1
1:50~100
Isotype
Rabbit Ig
Calculated MW
176442
Antigen Region
1591-1620
Antigen Source
HUMAN
Target/Specificity
This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1591~1620 amino acids from the C-terminal region of human ALK.
NCBI Accession
NP_004295.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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