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ALK Antibody (C-term)

ALK Antibody (C-term)

Item no.	ABC-AP7600b
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Adenocarcinoma Immunohistochemistry Primary Antibodies Astrocytoma
Type	Antibody Polyclonal
Applications	IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Morris, S.W., et al., Oncogene 14(18):2175-2188 (1997). Iwahara, T., et al., Oncogene 14(4):439-449 (1997). Morris, S.W., et al., Science 263(5151):1281-1284 (1994). Morris, S.W., et al., Oncogene 15, 2883-2883 (1997).
NCBI	NP_004295.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALK tyrosine kinase receptor,Anaplastic lymphoma kinase,CD246,ALK
Similar products	ALK, ALK tyrosine kinase receptor, CD246, Anaplastic lymphoma kinase
Available
Manufacturer - Category	Primary Antibodies; Cancer; Neuroscience; Anti-Kinome Antibodies
Manufacturer - Targets	This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1591~1620 amino acids from the C-terminal region of human ALK.
Bio Background	ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2; 5)(p23; q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB1513-1514
Gene Name	ALK {ECO:0000303\|PubMed:9174053, ECO:0000312\|HGNC:HGNC:427}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	176442
Antigen Source	HUMAN
Antigen Region	1591-1620
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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