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IGFBP3 Antibody (N-term)

ArtNr ABC-AP7641A
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Primary
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Applikationen WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IGFBP3, IGF-binding protein 3, IGFBP-3, IBP3, Insulin-like growth factor-binding protein 3, IBP-3
Lieferbar
Primary Accession
P17936
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
Bio References
Muzumdar, R.H., Diabetes 55 (10), 2788-2796 (2006)
Novosyadlyy, R., Growth Horm. IGF Res. 15 (5), 313-323 (2005)
Clonality
Polyclonal
Clone/Animal Names
RB08956
Gene ID
3486
Gene Name
IGFBP3
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of anti-IGFBP3 Antibody (N-term) (Cat. #AP7641a) in HepG2 cell line lysates (35ug/lane). IGFBP3(arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with IGFBP3 Antibody (N-term) (Cat.#AP7641a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Other Accession
P15473
Predicted
Rat
Isotype
Rabbit Ig
Calculated MW
31674
Antigen Region
163-193
Antigen Source
HUMAN
Target/Specificity
This IGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-193 amino acids from the N-terminal region of human IGFBP3.
NCBI Accession
NP_000589.2; NP_001013416.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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