Comparison

IGFBP3 Antibody (N-term)

Item no. ABC-AP7641A
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Applications WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products IGFBP3, IGF-binding protein 3, IGFBP-3, IBP3, Insulin-like growth factor-binding protein 3, IBP-3
Available
Primary Accession
P17936
Antigen Type
Synthetic Peptide
Application
IHC-P, WB
Bio Background
IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
Bio References
Muzumdar, R.H., Diabetes 55 (10), 2788-2796 (2006)
Novosyadlyy, R., Growth Horm. IGF Res. 15 (5), 313-323 (2005)
Clonality
Polyclonal
Clone/Animal Names
RB08956
Gene ID
3486
Gene Name
IGFBP3
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Western blot analysis of anti-IGFBP3 Antibody (N-term) (Cat. #AP7641a) in HepG2 cell line lysates (35ug/lane). IGFBP3(arrow) was detected using the purified Pab.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with IGFBP3 Antibody (N-term) (Cat.#AP7641a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2
IHC-P
Dilution image 2
1:10~50
Other Accession
P15473
Predicted
Rat
Isotype
Rabbit Ig
Calculated MW
31674
Antigen Region
163-193
Antigen Source
HUMAN
Target/Specificity
This IGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-193 amino acids from the N-terminal region of human IGFBP3.
NCBI Accession
NP_000589.2; NP_001013416.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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